A significant shift is underway in the world of ageing science, focusing on female biology to unravel long-held assumptions and uncover groundbreaking insights. This article explores the previously overlooked role of women in longevity research and the implications for healthier ageing for all. Delve into the impact of menopause on the ageing process, the accelerated ageing linked to ovarian function, and the potential breakthroughs in slowing down ageing using low-dose rapamycin. Discover how the X chromosome may hold the key to female resilience in the face of ageing challenges, shedding light on why women tend to live longer and healthier lives on average.