In a groundbreaking development, scientists from Tel Aviv University and the Israel Institute for Biological Research (IIBR) have successfully engineered the world’s first mRNA-based vaccine specifically targeting the deadly Yersinia pestis bacterium, notorious for causing plague outbreaks. The vaccine has exhibited exceptional effectiveness, reaching 100% success rates in animal trials aimed at combating pneumonic plague, a severe form of the disease. The research, spearheaded by Prof. Dan Peer and his team at Tel Aviv University in collaboration with experts from IIBR, represents a significant stride in addressing antibiotic-resistant threats posed by Yersinia pestis.