Harvard researchers have identified 17 modifiable factors significantly impacting stroke, dementia, and late-life depression. High blood pressure, kidney disease, and diabetes top the list. By emphasizing lifestyle changes and treatable conditions over genetic predispositions, the Brain Care Score helps track progress. Simple adjustments such as ensuring adequate sleep, engaging in brisk walking, timely treatment for hearing loss, maintaining a healthy diet, and stress management can substantially reduce risks. Learn more about the 17 modifiable factors that link to stroke, dementia, and late-life depression.