A groundbreaking study has unveiled that GLP-1 receptor agonists, including popular weight-loss and diabetes drugs like Ozempic, Wegovy, and Mounjaro, may significantly reduce the risk of developing dementia. The analysis, conducted by Irish researchers and published in JAMA Neurology, involved data from over 164,000 participants and found that these medications reduced the risk of memory-robbing disorders by up to 45 per cent. These findings not only open new avenues for neurological protection but also position GLP-1 drugs as powerful tools in both metabolic and cognitive health management. Researchers from the University of Galway reviewed 26 clinical trials involving 164,531 individuals—65% of whom were men, with an average age of 64. The participants were followed for an average of 31 months. Patients taking GLP-1 agonists such as semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro) were 45% less likely to develop dementia compared to those on other glucose-lowering medications.
